Why us – what makes us different.
Our competitive advantage is the ability to transfer technologies and know-how from the field of red biotech into green/white biotech. During previous projects, the founding members implemented, developed and advanced cutting-edge technologies for pharmaceutical production processes. This specific know-how is the core of the competitive advantage. Our direct and close cooperation with workshops allows efficient development cycles and quick prototyping.
We offer scientific excellence as many others do. But more importantly we turn scientific explanations into industrial solutions. Only transferable, implementable solutions allow to precipitate the benefits of the gained know how. To ensure highly efficient development routines Evologic follows 4 principles:
REPRODUCIBILITY THROUGH AUTOMATION
A lot of manual bench work is cumbersome and highly repetitive. As a matter of fact, humans are less reliable in repetitive tasks than machines. Generally spoken, there are more exciting tasks for humans than pipetting - like data analysis. Nevertheless, the decision which tasks to automate is delicate, since the effort for automatization is not to be underestimated. Commonly, we prioritize in respect to the contribution of the task to the total error of analysis to ensure an optimal effort/information ratio.
SPEED - PARALLELIZATION
Already Henry Ford used the synergies which occur if process steps are grouped and executed within an assembly line. In this respect, the parallelization of e.g. reactors allows to minimize the necessary time for setup and cleaning. Instead of executing steps as e.g. media preparation, sterilization, several times in a in a row, these steps can be combined if reactors are set up in parallel. This saves a lot of time which can be invested otherwise and helps to increase efficiency.
SCALABILITY – SCALE UP VS NUMBER UP
In the lab, a lot of improvised solutions can really speed things up. But it is of utmost importance that a given process is not optimized to perfection using a variety of custom made miniature solutions. Most importantly in bioprocess scalability must always stay in focus. As soon as during the experimental design for lab scale we constrain the design-space of process variables to the technical feasible space in target production scale. This ensures the transferability of the developed process to the final production unit and effectively helps to minimize scaling issues.
CELLS – PRODUCERS IN FOCUS
Scientific literature illustrates a long history of optimizing bioprocesses by merely optimizing input/output rates of the bioreactor. In contrast to a long history of regarding the "bioreactor" as productive entity, state of the art technologies allow us to take a closer look at a cellular level. This change of focus appears self-evident - the actual producer of a given product, are the cells/organism inside the bioreactor. This change of focus is correlated with an increased analytical effort, but promises significant increases in productivity.